|IMAGING INFORMATICS GROUP
PhD in Molecular and Cell Biology
Master of Technology in Knowledge Engineering
Phone: +65 64788269 (Office)
30 Biopolis Street, #07-01 Matrix Building
Republic of Singapore
- Cell and Developmental Biology
- 3D Time-Lapse microscopy
- Computer Vision
- Artificial Intelligence
Multidimensional Imaging in Drosophila Development
My group is interested in studying animal development using 3D time-lapse microscopy and computer vision. We observe fluorescently tagged protein in live Drosophila tissues using high-speed confocal microscopy. For instance, we trace cell lineages in embryos and follow the destruction and remodeling of muscles during metamorphosis. In our interdisciplinary research environment consisting of biologists, engineers and computer scientists, we develop computational tools for the automated quantification and interpretation of 3D time-lapse movies. A major part of our work focuses on image segmentation, feature extraction and object tracking.
- Place of Birth: Bensberg, Germany
- Nationality: German
- Marital Status: Married
- Master of Technology in Knowledge Engineering; Institute of Systems Science, National University of Singapore; awarded in 2004
- Ph.D. in Molecular and Cell Biology; Institute of Molecular & Cell Biology, National University of Singapore; awarded in 1998
- Diplombiologe (M.Sc.), Department of Biology, Faculty of Mathematics and Natural Sciences, University of Cologne; awarded in 1993
2007-present: Research Scientist; Bioinformatics Institute, Singapore
2004-2006: Research Fellow; Temasek LifeSciences Laboratory; Singapore
1998-2003: Research Fellow; Institute of Molecular & Cell Biology, Singapore
1993-1998: Assistant Research Officer; Institute of Molecular & Cell Biology, Singapore
1992-1993: Research Assistant; University of Cologne; Germany
- Wasser Martin, Zalina Bte Osman, Chia, William (2007). “EAST and Chromator control Muscle Destruction and Remodeling in Drosophila Metamorphosis”. Developmental Biology Vol. 2, 380-393.
- Wasser, Martin and Chia, William (2007). The extrachromosomal EAST Protein of Drosophila can associate with Polytene Chromosomes and regulate gene expression. PLoS ONE 2: e412.
- Wasser, Martin and Chia, William (2003). “The Drosophila EAST protein associates with a nuclear remnant during mitosis and constrains chromosome mobility.” Journal of Cell Science 116: 1733-1743.
- Wasser,Martin and Chia, William (2000). “The EAST protein of Drosophila controls an expandable nuclear endoskeleton.” Nature Cell Biology, Vol. 2, Issue 5, 268-275.
- Li, Peng, Yang, Xiaohang, Wasser,Martin, Cai, Yu and Chia, William (1997). “Inscuteable and Staufen are required for the asymmetric localisation and segregation of Prospero RNA during Drosophila neuroblast cell divisions.” Cell 90, 437-447.
- Georgias, Christine, Wasser, Martin and Hinz, Uwe (1997). “A basic-helix-loop-helix protein expressed in precursors of Drosophila longitudinal visceral muscles.” Mechanisms of Development, 69, 115-124.
2003: Best Project for the Master of Technology in Knowledge Engineering at the Institute of Systems Science, National University of Singapore. Title of the Project “Automatic Recognition and Identification of Drosophila Chromosomes”.