to the website of the Biophysical Modeling Group at the A*STAR Bioinformatics Institute.  The group uses a combination of biophysical and bioinformatics tools to study cell migration.  Cell migration is a critical process in every living organism, central to, for example, the morphogenesis of embryos, formation of tissues and organs, wound repair, as well as in less welcoming scenarios such as cancer metastasis.  Some of our current projects include the study of amoeboid modes of cancer cell invasion, collective modes of epithelial cell sheet migration, and

swimming and swarming modes of bacterial cell motility.

We hope that our approach will allow us to identify potential targets to perturb cell migration, which can eventually be translated into drugs to stop cancer cell invasion, promote wound and skin healing, or stop the aggregation of bacterial cells into biofilms.

We collaborate extensively with wet labs and welcome inquiries about collaborations regarding modeling.

Our research is supported by funding from A*STAR and the Mechanobiology Institute.




Keng-Hwee Chiam, Ph.D., Principal Investigator


Tel: +65 6478-8264

Address: 30 Biopolis St. #07-01, Singapore 138671, Singapore